INVOLVEMENT OF INTERNAL AND EXTERNAL MITOCHONDRIAL NADH DEHYDROGENASES IN YEAST CELLS RESPONSE TO HEAT SHOCK

Original title

УЧАСТИЕ ВНУТРЕННЕЙ И ВНЕШНИХ МИТОХОНДРИАЛЬНЫХ NADH ДЕГИДРОГЕНАЗ В ОТВЕТЕ КЛЕТОК ДРОЖЖЕЙ SACCHAROMYCES CEREVISIAE НА ТЕПЛОВОЙ ШОК

Authors

I.V. Fedoseeva, D.V. Pyatrikas, A.V. Stepanov, A.V. Fedyaeva, N.N. Varakina, E.G. Rikhvanov

Contact information

Siberian Institute of Plant Physiology and Biochemistry SB RAS, Irkutsk, Russia, Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра.

Pages

147-149

DOI

10.31255/978-5-94797-318-1-147-149

Abstract

Thermotolerance, induced thermotolerance, induction of Hsp104p synthesis and production of ROS in yeast cells with impaired mitochondrial NADH dehydrogenases were studied. The results obtained showed that Nde2p and Ndi1p play an important role in the yeast cell response to heat exposure. The heat shock causes the Ndi1p output and possibly Nde2p from the mitochondria to the cytosol, resulting in an imbalance between the protective program and the cell death program.